In this webinar, we will discuss four challenges to communicating successfully during the COVID-19 pandemic including: (1) the need for clear, consistent, credible and apolitical communication (CCCaP); (2) how various types of informational uncertainty challenge CCCaP; (3) how misinformation challenges CCCaP and how it can be addressed (and not addressed); and (4) looking ahead to the virus? demise with the development of a successful vaccine, public health campaigns must ready the public to accept vaccination especially in communities which have traditionally had low vaccination rates.