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Member Research & Reports

Member Research & Reports

UAB: Prediabetes and Risk for Cardiovascular Disease by Hypertension Status in Black Adults – The Jackson Heart Study

Recent studies have suggested that prediabetes is associated with an increased risk for cardiovascular disease (CVD) only among individuals with concomitant hypertension. Few data are available on whether the risk for CVD associated with prediabetes differs among black adults with versus without hypertension. This question is important given the high prevalence of both prediabetes and hypertension among black adults in the U.S.

A team of researchers collaborated on this study, including Dr. Paul Muntner, Dr. Byron Jaeger, Dr. Lisandro Colantonio, Dr. April Carson, Ms. Demetria Hubbard, Dr. Rikki Tanner, Ms. Swati Sakhuja, Department of Epidemiology, from the University of Alabama at Birmingham School of Public Health.

This paper examined the association between prediabetes and incident CVD and all-cause mortality among black adults with and without hypertension using data from the Jackson Heart Study (JHS). The JHS is a community‐based prospective cohort study designed to identify factors that explain the high rate of CVD among black adults and to find approaches for reducing this risk.

Regardless of hypertension status, prediabetes was not associated with an increased risk for CVD or all-cause mortality in this cohort of black adults. These findings suggest that black adults with hypertension may benefit from lifestyle and/or pharmacological interventions to lower their risk for CVD and all-cause mortality. Among black adults with prediabetes, interventions should be implemented to prevent the development of diabetes, which is a risk factor for CVD.

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