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School & Program Updates

School & Program Updates

Temple: Studying the Links between Sleep, Obesity and Type 2 Diabetes

Like snacking, pediatric sleep comes with its own recommendations and assumptions. According to the American Academy of Pediatrics (AAP) and the American Academy of Sleep Medicine, children should receive anywhere from nine to 16 hours of sleep per 24-hour period, depending on their age. While a new study by Dr. Chantelle Hart, associate professor of social and behavioral sciences and research scientist in Temple University’s Center for Obesity Research and Education (CORE), doesn’t question these guidelines, it does take a look at an often overlooked aspect: the quality of sleep, not the quantity.

Thanks to grants from the American Diabetes Association (ADA) and National Institutes of Health (NIH), Dr. Hart is exploring, through two studies, how children’s sleep patterns affect weight regulation and the risk of developing Type 2 diabetes. The studies represent a shift in direction from previous work in this area, which is typically observational and focuses on the quantity of sleep.

By contrast, Dr. Hart’s work uses randomized controlled study designs and focuses on the effects of sleep duration and consistent sleep patterns on glucose regulation. In addition, unlike other studies, she is looking at how better sleep, combined with improved eating and activity behaviors, affects weight regulation.

“Previously, we enhanced the number of hours children slept and stabilized the timing, and observed improvements in eating and activity behaviors in a short period of time,” said Dr. Hart. “But we cannot untangle which drove the observed changes in obesity-related risk factors.”

Dr. Hart’s ADA-funded study will enroll African-American children with overweight and obesity, a group at increased risk for developing Type 2 diabetes. All children will be asked to sleep as they normally do for a week. Then, each child follows a randomly chosen schedule for four weeks.

One group will stabilize their sleep patterns, meaning they’ll go to sleep and wake up at the same times each day, and increase their sleep duration by 90 minutes each night. Another will stabilize sleep and increase it by 45 minutes each night. A third only stabilizes their sleep pattern, and the fourth continues with their normal sleep habits. “Hopefully, we’ll have a signal of which approach may be helpful for decreasing diabetes risk in children,” said Dr. Hart.

Meanwhile, a separate study funded by a five-year, $3.78 million grant from the NIH assesses the relative efficacy of two approaches to weight regulation in school-aged children. While both studies examine the effect of sleep on diabetes risk, this study focuses more on the role sleep plays in weight regulation.

“There are potentially many ways sleep can affect obesity risk,” Dr. Hart explained. “In this study, we will be able to compare how improving children’s sleep alone, compared to improving sleep along with targeted eating and activity behaviors, affects weight regulation over 12 months.”

African-American children eight to 11 years old will be randomly assigned to one of two groups. Dr. Hart will ask children in the first group to increase the amount they sleep each night by approximately one hour. Children in a second group will be asked to increase their sleep and improve targeted eating and activity behaviors such as watching less television, drinking fewer sugar-sweetened beverages and increasing physical activity.

“We’re trying to determine if sleep is an important, novel strategy for weight regulation,” Dr. Hart explained. “We have some promising evidence from preliminary studies, and this new study will help determine if sleep, in and of itself or when combined with other effective strategies, is important.”

Read more news from the Center for Obesity Research and Education (CORE).