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Member Research & Reports

Member Research & Reports

Iowa: Researchers Investigate Role of Aspirin in Preventing Intracranial Aneurysm Rupture

University Iowa researchers conducted a database search to investigate whether aspirin can aid in the prevention of intracranial aneurysm rupture by hindering aneurysm growth. The researchers, including University of Iowa College of Public Health professor of epidemiology Dr. James Torner, identified 146 patients harboring a total of 375 intracranial aneurysms, five millimeters or less in diameter, that had been observed for at least five years.

The researchers found an association between aspirin use and a decreased rate of aneurysm growth. Growth is important in intracranial aneurysms because it increases the risk of aneurysm rupture.

In this study, all aneurysms observed to grow later underwent treatment. This occurred with 24 aneurysms. None of the observed aneurysms ruptured.

According to the Brain Aneurysm Foundation, in the United States an estimated 6.5 million people have an unruptured intracranial artery. Many small aneurysms do not cause symptoms and are unlikely to rupture. Each year, however, approximately 30,000 Americans experience aneurysm rupture, which can result in disability and even death.

The article, “Aspirin associated with decreased rate of intracranial aneurysm growth,” by Dr. Mario Zanaty, and colleagues, was published in the Journal of Neurosurgery.

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