A collaborative study including Ms. Nima Patel, alumni, and Dr. Robert Vogel, professor of biostatistics at Georgia Southern University Jiann-Ping Hsu College of Public Health, examine the concentrations and distribution of serum lipids in patients with PCa as compared with serum from controls. The results of prostate specific antigen (PSA) and digital rectal examination (DRE) screenings lead to both under and over treatment of prostate cancer (PCa). As such, there is an urgent need for the identification and evaluation of new markers for early diagnosis and disease prognosis. Studies have shown a link between PCa, lipids and lipid metabolism. The results of this study demonstrated that ePC 38:5, PC 40:3, and PC 42:4 may serve as early predictive serum markers for the presence of PCa.